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Study Shows Grapefruit Pulp May Reduce the Risk of Osteoporosis
Study Shows Grapefruit Pulp May Reduce the Risk of Osteoporosis
November 24, 2008 Author: David Gutierrez
Source: Natural News
Consumption of red grapefruit pulp may increase bone strength and reduce the risk of
osteoporosis, according to a study conducted by researchers from Texas A&M University
and published in the journal Nutrition.
Researchers castrated 42 male rats as a way to induce oxidative stress and to increase the
risk of osteoporosis. One-third of the rats were then fed a normal diet, one-third were fed
the same diet plus 5 percent red grapefruit pulp, while the final third were fed the same diet
plus 10 percent red grapefruit pulp.
After 60 days, the castrated rats on the normal diet showed significant decreases in
antioxidant status, bone mineral content and bone quality when compared with 14
uncastrated male rats. They also demonstrated increased calcium loss and higher levels of
urinary deoxypyridinoline, a marker of bone breakdown.
Decreased bone mineral content and bone quality are markers of a heightened risk of
osteoporosis, as are increased calcium loss and higher urinary deoxypyridinoline
concentrations.
Among the castrated rats whose diet was supplemented with grapefruit, urinary
deoxypyridinoline levels were lower than in the other castrated rats. While all the castrated
rats underwent decreases in the magnesium and calcium content of their bones, this
decrease was not as severe among the rats in the grapefruit pulp group.
Among the castrated rats not fed grapefruit pulp, lumbar calcium and magnesium levels
decreased 16 percent and 24 percent, respectively. Among the rats in the experimental
group, however, the respective decreases were only 10 and 16 percent. Likewise, femoral
calcium and magnesium levels dropped by 7 percent each among the non-grapefruit group,
but only 1 percent and 3 percent, respectively, in the grapefruit pulp groups.
The effects of grapefruit pulp were found to be dose-dependent.
An estimated 75 million people in Europe, Japan and the United States suffer from
osteoporosis. Four times as many women are affected as men.